In Vitro Antioxidant, Antiproliferative, and Phytochemical Study in Different Extracts of Nyctanthes arbortristis Flowers
Joint Authors
Setty, Oruganti H.
Avadhanula, Ravi K.
Khanapur, Manjulatha
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-20
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Nyctanthes arbortristis L.
(Oleaceae) is widely used in the Indian system of traditional medicine and is reported to have various biological activities.
The present study was intended to evaluate the antioxidant and antiproliferative activities of flower extracts of Nyctanthes arbortristis.
The shade dried flowers were extracted with 95% ethanol under sonication and the antioxidant activities were investigated using in vitro assays along with the determination of phytochemical constituents (total polyphenol and total flavonoid).
Arborside C and β-monogentiobioside ester of α-Crocetin were identified in crude active extracts through LCMS/MS analysis.
The antiproliferative activity was carried out by MTT assay by employing different human cancer cell lines.
The lowest IC50 value of 24.56 ± 6.63 μg/mL was observed against Colo 205 cell line.
The extract exhibited significant antioxidant and antiproliferative properties and the observed biological activities in this study provide scientific validation of ethnomedicinal use of this plant.
American Psychological Association (APA)
Khanapur, Manjulatha& Avadhanula, Ravi K.& Setty, Oruganti H.. 2014. In Vitro Antioxidant, Antiproliferative, and Phytochemical Study in Different Extracts of Nyctanthes arbortristis Flowers. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-460845
Modern Language Association (MLA)
Khanapur, Manjulatha…[et al.]. In Vitro Antioxidant, Antiproliferative, and Phytochemical Study in Different Extracts of Nyctanthes arbortristis Flowers. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-460845
American Medical Association (AMA)
Khanapur, Manjulatha& Avadhanula, Ravi K.& Setty, Oruganti H.. In Vitro Antioxidant, Antiproliferative, and Phytochemical Study in Different Extracts of Nyctanthes arbortristis Flowers. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-460845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460845