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Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA Compared to Matched Controls : A GPRD Analysis
Joint Authors
Hodgson, Elizabeth
Nelson, Jeanenne J.
Shukla, Amit
Li, Haojie
Watson, Louise
Source
Journal of Cancer Epidemiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-11
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Comorbidity influences screening practice, treatment choice, quality of life, and survival.
The presence of comorbidities and medication use could place patients at greater risks of adverse effects from certain interventions.
We conducted a longitudinal cohort study in the General Practice Research Database to better understand comorbidities and medication use in men with or at risk of prostate cancer (CaP).
Compared with men with similar age but no CaP, CaP patients had higher incidence of urinary tract infection, impotence and breast disorder, and 2.6-fold higher all-cause mortality.
Among men with elevated prostate-specific antigen (PSA) but no CaP, the mortality rates were slightly lower, and fewer differences in comorbidities and medication use were noted compared to men without elevated PSA.
Many prevalent comorbidities and medications were consistent across groups and are typical of an older male population.
These real-world data are broadly applicable throughout the drug development cycle and subsequent patient management.
American Psychological Association (APA)
Li, Haojie& Hodgson, Elizabeth& Watson, Louise& Shukla, Amit& Nelson, Jeanenne J.. 2012. Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA Compared to Matched Controls : A GPRD Analysis. Journal of Cancer Epidemiology،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-460899
Modern Language Association (MLA)
Li, Haojie…[et al.]. Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA Compared to Matched Controls : A GPRD Analysis. Journal of Cancer Epidemiology No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-460899
American Medical Association (AMA)
Li, Haojie& Hodgson, Elizabeth& Watson, Louise& Shukla, Amit& Nelson, Jeanenne J.. Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA Compared to Matched Controls : A GPRD Analysis. Journal of Cancer Epidemiology. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-460899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460899