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Fall in Vitamin D Levels during Hospitalization in Children
Joint Authors
Kumar, Suresh
Dayal, Devi
Kumar, Rakesh
Singh, Meenu
Sachdeva, Naresh
Singhi, Sunit C.
Source
International Journal of Pediatrics
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Plasma levels of 25-hydroxyvitamin D [25(OH)D] were measured by competitive Electrochemiluminescence Immunoassay (ECLIA) in 92 children (67 boys, 25 girls) aged 3 months to 12 years at admission to hospital (timepoint 1, T1) and at discharge (timepoint 2, T2).
There was a significant fall in the mean 25(OH)D from T1 (71.87 ± 27.25 nmol/L) to T2 (49.03 ± 22.25 nmol/L) (mean change = 22.84 nmol/L, P value = 0.0004).
Proportion of patients having VDD (levels <50 nmol/L) at admission (25%, 23/92) increased significantly at the time of discharge (51.09%, 47/92) (P=0.0004).
There was a trend towards longer duration of hospital stay, requirement of ventilation and inotropes, development of healthcare-associated infection, and mortality in vitamin D deficient as compared to nondeficient patients though the difference was statistically insignificant.
In conclusion, vitamin D levels fall significantly and should be monitored during hospital stay in children.
Large clinical studies are needed to prospectively evaluate the effect of vitamin D supplementation in vitamin D deficient hospitalized children on various disease outcome parameters.
American Psychological Association (APA)
Dayal, Devi& Kumar, Suresh& Sachdeva, Naresh& Kumar, Rakesh& Singh, Meenu& Singhi, Sunit C.. 2014. Fall in Vitamin D Levels during Hospitalization in Children. International Journal of Pediatrics،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-460918
Modern Language Association (MLA)
Dayal, Devi…[et al.]. Fall in Vitamin D Levels during Hospitalization in Children. International Journal of Pediatrics No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-460918
American Medical Association (AMA)
Dayal, Devi& Kumar, Suresh& Sachdeva, Naresh& Kumar, Rakesh& Singh, Meenu& Singhi, Sunit C.. Fall in Vitamin D Levels during Hospitalization in Children. International Journal of Pediatrics. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-460918
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460918