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Biclonal IgD and IgM Plasma Cell Myeloma : A Report of Two Cases and a Literature Review
Joint Authors
Roth, Christine G.
Chen, Zhongchuan W.
Kotsikogianni, Ioanna
Rollins-Raval, Marian A.
Raval, Jay S.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Biclonal plasma cell myelomas producing two different isotypes of immunoglobulins are extremely rare entities; to date, the combination of IgD and IgM secretion by a biclonal plasma cell myeloma has not been reported.
Bone marrow biopsy immunohistochemical studies in two cases revealed neoplastic plasma cells coexpressing IgD and IgM, but serum protein electrophoresis identified only the IgM monoclonal paraprotein in both cases.
Biclonal plasma cell myelomas, while currently not well characterized in terms of their clinical behavior, should be distinguished from B-cell lymphoma with plasmacytic differentiation, given the different therapeutic implications.
Both cases reported herein demonstrated chemotherapy-resistant clinical courses.
American Psychological Association (APA)
Chen, Zhongchuan W.& Kotsikogianni, Ioanna& Raval, Jay S.& Roth, Christine G.& Rollins-Raval, Marian A.. 2013. Biclonal IgD and IgM Plasma Cell Myeloma : A Report of Two Cases and a Literature Review. Case Reports in Hematology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-461018
Modern Language Association (MLA)
Chen, Zhongchuan W.…[et al.]. Biclonal IgD and IgM Plasma Cell Myeloma : A Report of Two Cases and a Literature Review. Case Reports in Hematology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-461018
American Medical Association (AMA)
Chen, Zhongchuan W.& Kotsikogianni, Ioanna& Raval, Jay S.& Roth, Christine G.& Rollins-Raval, Marian A.. Biclonal IgD and IgM Plasma Cell Myeloma : A Report of Two Cases and a Literature Review. Case Reports in Hematology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-461018
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461018