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Patterns of Cancer Genetic Testing : A Randomized Survey of Oregon Clinicians
Joint Authors
Horn, Tara
Elliott, Debi
Leman, Richard F.
Johnson, Amber
Zlot, Amy I.
Silvey, Kerry
Cox, Summer L.
Source
Journal of Cancer Epidemiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Introduction.
Appropriate use of genetic tests for population-based cancer screening, diagnosis of inherited cancers, and guidance of cancer treatment can improve health outcomes.
We investigated clinicians’ use and knowledge of eight breast, ovarian, and colorectal cancer genetic tests.
Methods.
We conducted a randomized survey of 2,191 Oregon providers, asking about their experience with fecal DNA, OncoVue, BRCA, MMR, CYP2D6, tumor gene expression profiling, UGT1A1, and KRAS.
Results.
Clinicians reported low confidence in their knowledge of medical genetics; most confident were OB-GYNs and specialists.
Clinicians were more likely to have ordered/recommended BRCA and MMR than the other tests, and OB-GYNs were twice as likely to have ordered/recommended BRCA testing than primary care providers.
Less than 10% of providers ordered/recommended OncoVue, fecal DNA, CYP2D6, or UGT1A1; less than 30% ordered/recommended tumor gene expression profiles or KRAS.
The most common reason for not ordering/recommending these tests was lack of familiarity.
Conclusions.
Use of appropriate, evidence-based testing can help reduce incidence and mortality of certain cancers, but these tests need to be better integrated into clinical practice.
Continued evaluation of emerging technologies, dissemination of findings, and an increase in provider confidence and knowledge are necessary to achieve this end.
American Psychological Association (APA)
Cox, Summer L.& Zlot, Amy I.& Silvey, Kerry& Elliott, Debi& Horn, Tara& Johnson, Amber…[et al.]. 2012. Patterns of Cancer Genetic Testing : A Randomized Survey of Oregon Clinicians. Journal of Cancer Epidemiology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-461162
Modern Language Association (MLA)
Cox, Summer L.…[et al.]. Patterns of Cancer Genetic Testing : A Randomized Survey of Oregon Clinicians. Journal of Cancer Epidemiology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-461162
American Medical Association (AMA)
Cox, Summer L.& Zlot, Amy I.& Silvey, Kerry& Elliott, Debi& Horn, Tara& Johnson, Amber…[et al.]. Patterns of Cancer Genetic Testing : A Randomized Survey of Oregon Clinicians. Journal of Cancer Epidemiology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-461162
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461162