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Periconceptional Folate Deficiency and Implications in Neural Tube Defects
Joint Authors
Joyeux, L.
Safi, Joelle
Chalouhi, G. E.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Nutritional deficiencies are preventable etiological and epigenetic factors causing congenital abnormalities, first cause of infant mortality.
Folate deficiency has a well-established teratogenic effect, leading to an increasing risk of neural tube defects.
This paper highlights the most recent medical literature about folate deficiency, be it maternal or paternal.
It then focuses on associated deficiencies as nutritional deficiencies are multiple and interrelated.
Observational and interventional studies have all been consistent with a 50–70% protective effect of adequate women consumption of folates on neural tube defects.
Since strategies to modify women’s dietary habits and vitamin use have achieved little progress, scientific as well as political effort is mandatory in order to implement global preventive public health strategies aimed at improving the alimentation of women in reproductive age, especially folic acid supplementation.
Even with the recent breakthrough of fetal surgery for myelomeningocele, the emphasis should still be on prevention as the best practice rather than treatment of neural tube defects.
American Psychological Association (APA)
Safi, Joelle& Joyeux, L.& Chalouhi, G. E.. 2012. Periconceptional Folate Deficiency and Implications in Neural Tube Defects. Journal of Pregnancy،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-461201
Modern Language Association (MLA)
Safi, Joelle…[et al.]. Periconceptional Folate Deficiency and Implications in Neural Tube Defects. Journal of Pregnancy No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-461201
American Medical Association (AMA)
Safi, Joelle& Joyeux, L.& Chalouhi, G. E.. Periconceptional Folate Deficiency and Implications in Neural Tube Defects. Journal of Pregnancy. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-461201
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461201