Botulinum Toxin Injections for Simple Partial Motor Seizures Associated with Pain

Joint Authors

Mader, Edward C.
Fisch, Bruce J.
Olejniczak, Piotr W.
Villemarette-Pittman, Nicole R.
Carey, Michael E.

Source

Case Reports in Medicine

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-05-31

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Medicine

Abstract EN

Intractable epilepsy with painful partial motor seizures is a relatively rare and difficult disorder to treat.

We evaluated the usefulness of botulinum toxin to reduce ictal pain.

Two patients received two or four botulinum toxin (BTX) injections at one-to-two-month intervals.

Patient 1 had painful seizures of the right arm and hand.

Patient 2 had painful seizures involving the left foot and leg.

Injections were discontinued after improved seizure control following resective surgery.

Both patients received significant pain relief from the injections with analgesia lasting at least two months.

Seizure severity was reduced, but seizure frequency and duration were unaffected.

For these patients, BTX was effective in temporarily relieving pain associated with muscle contraction in simple partial motor seizures.

Our findings do not support the hypothesis that modulation of motor end-organ feedback affects focal seizure generation.

BTX is a safe and reversible treatment that should be considered as part of adjunctive therapy after failure to achieve control of painful partial motor seizures.

American Psychological Association (APA)

Mader, Edward C.& Fisch, Bruce J.& Villemarette-Pittman, Nicole R.& Olejniczak, Piotr W.& Carey, Michael E.. 2012. Botulinum Toxin Injections for Simple Partial Motor Seizures Associated with Pain. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-461212

Modern Language Association (MLA)

Mader, Edward C.…[et al.]. Botulinum Toxin Injections for Simple Partial Motor Seizures Associated with Pain. Case Reports in Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-461212

American Medical Association (AMA)

Mader, Edward C.& Fisch, Bruce J.& Villemarette-Pittman, Nicole R.& Olejniczak, Piotr W.& Carey, Michael E.. Botulinum Toxin Injections for Simple Partial Motor Seizures Associated with Pain. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-461212

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-461212