Self-Expanding Metal Stenting for Palliation of Patients with Malignant Colonic Obstruction : Effectiveness and Efficacy on 255 Patients with 12-Month's Follow-up
Joint Authors
Goldberg, Paul
González-Huix, Ferran
Registry Group, The WallFlex Colonic
Xinopoulos, Dimitrios
Vandervoort, Jo G.
Meisner, Søren
Repici, Alessandro
Grund, Karl E.
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Self-expanding metal stents can alleviate malignant colonic obstruction in incurable patients and avoid palliative stoma surgery.
Objective.
Evaluate stent effectiveness and safety on palliation of patients with malignant colorectal strictures.
Design.
Two prospective, one Spanish and one global, multicenter studies.
Settings.
39 centers (22 academic, 17 community hospitals) from 13 countries.
Patients.
A total of 257 patients were enrolled, and 255 patients were treated with a WallFlex uncovered enteral colonic stent.
Follow-up was up to 12 months or until death or retreatment.
Interventions(s).
Self-expanding metal stent placement.
Main Outcome Measures.
Procedural success, clinical success, and safety.
Results.
Procedural success was 98.4% (251).
Clinical success rates were 87.8% at 30 days, 89.7% at 3 months, 92.8% at 6 months, and 96% at 12 months.
Overall perforation rate was 5.1%.
Overall migration rate was 5.5%.
Overall death rate during follow-up was 48.6% (124), with 67.7% of deaths related to the patient’s colorectal cancer, unrelated in 32.3%.
Only 2 deaths were related to the stent or procedure.
Limitations.
No control group.
Conclusions.
The primary palliative option for patients with malignant colonic obstruction should be self-expanding metal stent placement due to high rates of technical success and efficacy in symptom palliation and few complications.
American Psychological Association (APA)
Meisner, Søren& González-Huix, Ferran& Vandervoort, Jo G.& Repici, Alessandro& Xinopoulos, Dimitrios& Grund, Karl E.…[et al.]. 2012. Self-Expanding Metal Stenting for Palliation of Patients with Malignant Colonic Obstruction : Effectiveness and Efficacy on 255 Patients with 12-Month's Follow-up. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461314
Modern Language Association (MLA)
Meisner, Søren…[et al.]. Self-Expanding Metal Stenting for Palliation of Patients with Malignant Colonic Obstruction : Effectiveness and Efficacy on 255 Patients with 12-Month's Follow-up. Gastroenterology Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-461314
American Medical Association (AMA)
Meisner, Søren& González-Huix, Ferran& Vandervoort, Jo G.& Repici, Alessandro& Xinopoulos, Dimitrios& Grund, Karl E.…[et al.]. Self-Expanding Metal Stenting for Palliation of Patients with Malignant Colonic Obstruction : Effectiveness and Efficacy on 255 Patients with 12-Month's Follow-up. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461314
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461314