Transformation of a Cutaneous Follicle Center Lymphoma to a Diffuse Large B-Cell Lymphoma—An Unusual Presentation

Joint Authors

Baptista, J.
Diamantino, F.
Sebastião, M.
Gameiro, P.
Farinha, P.
Dias Coelho, Joana
Costa, I.

Source

Case Reports in Medicine

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-05-31

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Medicine

Abstract EN

Primary cutaneous follicle center lymphoma (PCFCL) is characterized by a proliferation of follicle center cells in the skin.

A definitive diagnosis is frequently delayed because of difficulties in interpretation of the histopathologic findings.

It has an excellent prognosis with a 5-year survival over 95% and its risk of transformation has not been established.

We describe a case report of man with a gastric diffuse large B-cell lymphoma (DLBCL) referred to our clinic because of nodules in the back that had gradually developed over a period of 10 years.

A biopsy performed 3 years before was interpreted as reactive follicular hyperplasia.

A new skin biopsy revealed a diffuse large B-cell lymphoma and immunoglobulin heavy chain gene rearrangements from the initial skin biopsy (PCBCL) and the DLBCL gastric biopsy were studied by polymerase chain reaction and an identical clonal rearrangement was detected which was highly suggestive of a transformation lymphoma.

American Psychological Association (APA)

Dias Coelho, Joana& Diamantino, F.& Costa, I.& Farinha, P.& Gameiro, P.& Sebastião, M.…[et al.]. 2010. Transformation of a Cutaneous Follicle Center Lymphoma to a Diffuse Large B-Cell Lymphoma—An Unusual Presentation. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-461337

Modern Language Association (MLA)

Dias Coelho, Joana…[et al.]. Transformation of a Cutaneous Follicle Center Lymphoma to a Diffuse Large B-Cell Lymphoma—An Unusual Presentation. Case Reports in Medicine No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-461337

American Medical Association (AMA)

Dias Coelho, Joana& Diamantino, F.& Costa, I.& Farinha, P.& Gameiro, P.& Sebastião, M.…[et al.]. Transformation of a Cutaneous Follicle Center Lymphoma to a Diffuse Large B-Cell Lymphoma—An Unusual Presentation. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-461337

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-461337