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Signalling Molecules in the Urothelium
Joint Authors
Winder, Michael
Zupančič, Daša
Tobin, Gunnar
Romih, Rok
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-10
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The urothelium was long considered to be a silent barrier protecting the body from the toxic effects of urine.
However, today a number of dynamic abilities of the urothelium are well recognized, including its ability to act as a sensor of the intravesical environment.
During recent years several pathways of these urothelial abilities have been proposed and a major part of these pathways includes release of signalling molecules.
It is now evident that the urothelium represents only one part of the sensory web.
Urinary bladder signalling is finely tuned machinery of signalling molecules, acting in autocrine and paracrine manner, and their receptors are specifically distributed among different types of cells in the urinary bladder.
In the present review the current knowledge of the formation, release, and signalling effects of urothelial acetylcholine, ATP, adenosine, and nitric oxide in health and disease is discussed.
American Psychological Association (APA)
Winder, Michael& Tobin, Gunnar& Zupančič, Daša& Romih, Rok. 2014. Signalling Molecules in the Urothelium. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-461406
Modern Language Association (MLA)
Winder, Michael…[et al.]. Signalling Molecules in the Urothelium. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-461406
American Medical Association (AMA)
Winder, Michael& Tobin, Gunnar& Zupančič, Daša& Romih, Rok. Signalling Molecules in the Urothelium. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-461406
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461406