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What Is the de-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI
Joint Authors
Yang, Yang
Zhu, Yuanqiang
von Deneen, Karen M.
Jin, Lingmin
Sun, Jinbo
Tian, Jie
Qin, Wei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
de-qi, comprising mostly subjective sensations during acupuncture, is traditionally considered as a very important component for the possible therapeutic effects of acupuncture.
However, the neural correlates of de-qi are still unclear.
In this paper, we reviewed previous fMRI studies from the viewpoint of the neural responses of de-qi.
We searched on Pubmed and identified 111 papers.
Fourteen studies distinguishing de-qi and sharp pain and eight studies with the mixed sensations were included in further discussions.
We found that the blood oxygenation level-dependent (BOLD) responses associated with de-qi were activation dominated, mainly around cortical areas relevant to the processing of somatosensory or pain signals.
More intense and extensive activations were shown for the mixed sensations.
Specific activations of sharp pain were also shown.
Similar BOLD response patterns between de-qi evoked by acupuncture stimulation and de-qi-like sensations evoked by deep pain stimulation were shown.
We reckon that a standardized method of qualification and quantification of de-qi, deeper understanding of grouping strategy of de-qi and sharp pain, and making deep pain stimulation as a control, as well as a series of improvements in the statistical method, are crucial factors for revealing the neural correlates of de-qi and neural mechanisms of acupuncture.
American Psychological Association (APA)
Sun, Jinbo& Zhu, Yuanqiang& Yang, Yang& Jin, Lingmin& von Deneen, Karen M.& Qin, Wei…[et al.]. 2013. What Is the de-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-461451
Modern Language Association (MLA)
Sun, Jinbo…[et al.]. What Is the de-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-461451
American Medical Association (AMA)
Sun, Jinbo& Zhu, Yuanqiang& Yang, Yang& Jin, Lingmin& von Deneen, Karen M.& Qin, Wei…[et al.]. What Is the de-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-461451
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461451