Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease
Joint Authors
Philippens, Ingrid
‘t Hart, Bert A.
Copray, Sjef
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Accumulating evidence suggests that inflammatory mediators secreted by activated resident or infiltrated innate immune cells have a significant impact on the pathogenesis of neurodegenerative diseases.
This may imply that patients affected by a neurodegenerative disease may benefit from treatment with selective inhibitors of innate immune activity.
Here we review the therapeutic potential of apocynin, an essentially nontoxic phenolic compound isolated from the medicinal plant Jatropha multifida.
Apocynin is a selective inhibitor of the phagocyte NADPH oxidase Nox2 that can be applied orally and is remarkably effective at low dose.
American Psychological Association (APA)
‘t Hart, Bert A.& Copray, Sjef& Philippens, Ingrid. 2014. Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-461469
Modern Language Association (MLA)
‘t Hart, Bert A.…[et al.]. Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-461469
American Medical Association (AMA)
‘t Hart, Bert A.& Copray, Sjef& Philippens, Ingrid. Apocynin, a Low Molecular Oral Treatment for Neurodegenerative Disease. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-461469
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461469