Neonatal Lupus Erythematosus
Joint Authors
Hon, Kam-Lun Ellis
Leung, Alexander K. C.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Neonatal lupus erythematosus (NLE) refers to a clinical spectrum of cutaneous, cardiac, and systemic abnormalities observed in newborn infants whose mothers have autoantibodies against Ro/SSA and La/SSB.
The condition is rare and usually benign and self-limited but sometimes may be associated with serious sequelae.
We review the pathophysiology, clinical features, and management of infants with this condition.
Neonates with NLE should be managed at a tertiary care center.
Multidisciplinary team involvement may also be indicated.
In mothers with anti-Ro/SSA and/or anti-La/SSB antibodies and infants with congenital heart block, the risk of recurrence in subsequent offspring is 17–25%.
Therefore, careful monitoring of subsequent pregnancies with serial ultrasonography and echocardiography is essential.
American Psychological Association (APA)
Hon, Kam-Lun Ellis& Leung, Alexander K. C.. 2012. Neonatal Lupus Erythematosus. Autoimmune Diseases،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461579
Modern Language Association (MLA)
Hon, Kam-Lun Ellis& Leung, Alexander K. C.. Neonatal Lupus Erythematosus. Autoimmune Diseases No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-461579
American Medical Association (AMA)
Hon, Kam-Lun Ellis& Leung, Alexander K. C.. Neonatal Lupus Erythematosus. Autoimmune Diseases. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461579
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461579
