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New Perspectives on Antiacne Plant Drugs : Contribution to Modern Therapeutics
Joint Authors
Yadav, Narayan Prasad
Srivastava, Shruti
Sinha, Priyam
Mishra, Nidhi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-23
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Acne is a common but serious skin disease, which affects approximately 80% adolescents and young adults in 11–30 age group.
42.5% of men and 50.9% of women continue to suffer from this disease into their twenties.
Bacterial resistance is now at the alarming stage due to the irrational use of antibiotics.
Hence, search for new lead molecule/bioactive and rational delivery of the existing drug (for better therapeutic effect) to the site of action is the need of the hour.
Plants and plant-derived products have been an integral part of health care system since time immemorial.
Therefore, plants that are currently used for the treatment of acne and those with a high potential are summarized in the present review.
Most active plant extracts, namely, P.
granatum, M.
alba, A.
anomala, and M.
aquifolium exhibit minimum inhibitory concentration (MIC) in the range of 4–50 µg/mL against P.
acnes, while aromatic oils of C.
obovoides, C.
natsudaidai, C.
japonica, and C.
nardus possess MICs 0.005–0.6 μL/mL and phytomolecules such as rhodomyrtone, pulsaquinone, hydropulsaquinone, honokiol, magnolol, xanthohumol lupulones, chebulagic acid and rhinacanthin-C show MIC in the range of 0.5–12.5 μg/mL.
Novel drug delivery strategies of important plant leads in the treatment of acne have also been discussed.
American Psychological Association (APA)
Sinha, Priyam& Srivastava, Shruti& Mishra, Nidhi& Yadav, Narayan Prasad. 2014. New Perspectives on Antiacne Plant Drugs : Contribution to Modern Therapeutics. BioMed Research International،Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-461586
Modern Language Association (MLA)
Sinha, Priyam…[et al.]. New Perspectives on Antiacne Plant Drugs : Contribution to Modern Therapeutics. BioMed Research International No. 2014 (2014), pp.1-19.
https://search.emarefa.net/detail/BIM-461586
American Medical Association (AMA)
Sinha, Priyam& Srivastava, Shruti& Mishra, Nidhi& Yadav, Narayan Prasad. New Perspectives on Antiacne Plant Drugs : Contribution to Modern Therapeutics. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-461586
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461586