Atypical Neurofibroma and Osteosclerotic Metastasis
Joint Authors
Thukral, Anubhav
Varyani, Neeraj
Gupta, Kailash Kumar
Garg, Sunny
Tandon, Ravi
Tripathi, Kamlakar
Source
Case Reports in Oncological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
35-year-old male presented with multiple swellings in left leg, headache, weakness of limbs for 4 months, and blurring of vision for the last 15 days.
On examination, he was pale, cachexic with generalized lymphadenopathy and lower motor neuron type weakness of limbs sparing right upper limb.
Blood investigations showed anemia with high alkaline phosphatase.
Chest radiograph revealed osteosclerotic metastatic lesion in humerus.
Biopsy of leg lesion revealed atypical neurofibroma.
Computed tomography (CT) of thorax revealed osteoblastic metastasis.
Bone marrow aspiration showed cells with round to oval nuclei, fine granular chromatin with large central prominent nucleoli and eosinophilic cytoplasm with acini formation.
Magnetic resonance imaging (MRI) of brain and spinal cord defined metastatic leptomeningeal deposits.
Cerebrospinal fluid (CSF) cytology was positive for malignant cells.
Gastroscopy showed an ulceroinfiltrative growth from stomach which on histopathology revealed diffuse adenocarcinoma.
Palliative treatment was given with intrathecal methotrexate and systemic corticosteroid with chemotherapy.
Patient’s symptom improved drastically, but we lost him to followup.
American Psychological Association (APA)
Varyani, Neeraj& Thukral, Anubhav& Garg, Sunny& Gupta, Kailash Kumar& Tandon, Ravi& Tripathi, Kamlakar. 2012. Atypical Neurofibroma and Osteosclerotic Metastasis. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-461598
Modern Language Association (MLA)
Varyani, Neeraj…[et al.]. Atypical Neurofibroma and Osteosclerotic Metastasis. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-461598
American Medical Association (AMA)
Varyani, Neeraj& Thukral, Anubhav& Garg, Sunny& Gupta, Kailash Kumar& Tandon, Ravi& Tripathi, Kamlakar. Atypical Neurofibroma and Osteosclerotic Metastasis. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-461598
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461598