Potency of Fish Collagen as a Scaffold for Regenerative Medicine
Joint Authors
Yamada, Shizuka
Yanagiguchi, Kajiro
Hayashi, Yoshihiko
Ikeda, Takeshi
Yamamoto, Kouhei
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Cells, growth factors, and scaffold are the crucial factors for tissue engineering.
Recently, scaffolds consisting of natural polymers, such as collagen and gelatin, bioabsorbable synthetic polymers, such as polylactic acid and polyglycolic acid, and inorganic materials, such as hydroxyapatite, as well as composite materials have been rapidly developed.
In particular, collagen is the most promising material for tissue engineering due to its biocompatibility and biodegradability.
Collagen contains specific cell adhesion domains, including the arginine-glycine-aspartic acid (RGD) motif.
After the integrin receptor on the cell surface binds to the RGD motif on the collagen molecule, cell adhesion is actively induced.
This interaction contributes to the promotion of cell growth and differentiation and the regulation of various cell functions.
However, it is difficult to use a pure collagen scaffold as a tissue engineering material due to its low mechanical strength.
In order to make up for this disadvantage, collagen scaffolds are often modified using a cross-linker, such as gamma irradiation and carbodiimide.
Taking into account the possibility of zoonosis, a variety of recent reports have been documented using fish collagen scaffolds.
We herein review the potency of fish collagen scaffolds as well as associated problems to be addressed for use in regenerative medicine.
American Psychological Association (APA)
Yamada, Shizuka& Yamamoto, Kouhei& Ikeda, Takeshi& Yanagiguchi, Kajiro& Hayashi, Yoshihiko. 2014. Potency of Fish Collagen as a Scaffold for Regenerative Medicine. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-461744
Modern Language Association (MLA)
Yamada, Shizuka…[et al.]. Potency of Fish Collagen as a Scaffold for Regenerative Medicine. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-461744
American Medical Association (AMA)
Yamada, Shizuka& Yamamoto, Kouhei& Ikeda, Takeshi& Yanagiguchi, Kajiro& Hayashi, Yoshihiko. Potency of Fish Collagen as a Scaffold for Regenerative Medicine. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-461744
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461744