Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer

Abstract EN

Paraneoplastic syndrome associated with prostate cancer is extremely rare.

We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.

After a few detailed examinations, prostate cancer was diagnosed.

After treatment with bicalutamide and leuprolide, the patient’s symptoms and laboratory abnormalities were reversed.

Cholestatic jaundice was regarded as a paraneoplastic manifestation in this patient.

The patient remains symptom-free after 14-month followup.

Paraneoplastic syndrome should be considered in case of cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.