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Hydatid Cyst Protoscolices Induce Cell Death in WEHI-164 Fibrosarcoma Cells and Inhibit the Proliferation of Baby Hamster Kidney Fibroblasts In Vitro
Joint Authors
Shirzad, Hedayatollah
Khorami, Soliman
Taji, Fatomeh
Yousofi, Mortaza
Soozangar, Narges
Yousofi Darani, Hossein
Source
Journal of Parasitology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Both in vitro and in vivo models have demonstrated that some parasites can interfere with tumor cell growth.
The present study investigates the anticancer activity of hydatid cyst protoscolices on WEHI-164 fibrosarcoma cells and baby hamster kidney (BHK) fibroblast cells in vitro.
Those above two cell types were treated with live hydatid cyst protoscolices or left untreated for control groups.
After 48 h, lactate dehydrogenase (LDH) and cell counts were assayed for both treated cells and control groups.
Following treatment with hydatid cyst protoscolices, cell proliferation of both cell types was inhibited, and lysis of fibrosarcoma cells increased.
Based on these results, it appears that hydatid cyst protoscolices have strong anticancer activity, and additional studies are needed to further clarify the mechanisms of this activity.
American Psychological Association (APA)
Yousofi Darani, Hossein& Soozangar, Narges& Khorami, Soliman& Taji, Fatomeh& Yousofi, Mortaza& Shirzad, Hedayatollah. 2012. Hydatid Cyst Protoscolices Induce Cell Death in WEHI-164 Fibrosarcoma Cells and Inhibit the Proliferation of Baby Hamster Kidney Fibroblasts In Vitro. Journal of Parasitology Research،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-461843
Modern Language Association (MLA)
Yousofi Darani, Hossein…[et al.]. Hydatid Cyst Protoscolices Induce Cell Death in WEHI-164 Fibrosarcoma Cells and Inhibit the Proliferation of Baby Hamster Kidney Fibroblasts In Vitro. Journal of Parasitology Research No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-461843
American Medical Association (AMA)
Yousofi Darani, Hossein& Soozangar, Narges& Khorami, Soliman& Taji, Fatomeh& Yousofi, Mortaza& Shirzad, Hedayatollah. Hydatid Cyst Protoscolices Induce Cell Death in WEHI-164 Fibrosarcoma Cells and Inhibit the Proliferation of Baby Hamster Kidney Fibroblasts In Vitro. Journal of Parasitology Research. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-461843
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461843