Amauroderma rugosum (Blume & T. Nees) Torrend : Nutritional Composition and Antioxidant and Potential Anti-Inflammatory Properties
Joint Authors
Kanagasabapathy, Gowri
Tan, Yee-Shin
Chan, Pui-Mun
Kuppusamy, Umah Rani
Sabaratnam, Vikineswary
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Amauroderma rugosum is a wild mushroom that is worn as a necklace by the indigenous communities in Malaysia to prevent fits and incessant crying by babies.
The aim of this study was to investigate the nutritive composition and antioxidant potential and anti-inflammatory effects of A.
rugosum extracts on LPS-stimulated RAW264.7 cells.
Nutritional analysis of freeze-dried mycelia of A.
rugosum (KUM 61131) from submerged culture indicated a predominant presence of carbohydrates, proteins, dietary fibre, phosphorus, potassium, and sodium.
The ethanol crude extract (EE), its hexane (HF), ethyl acetate (EAF), and aqueous (AF) fractions of mycelia of A.
rugosum grown in submerged culture were evaluated for antioxidant potential and anti-inflammatory effects.
EAF exhibited the highest total phenolic content and the strongest antioxidant activity based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays.
HF showed dose-dependent inhibition of NO production in LPS-stimulated RAW264.7 cells and NO radical scavenging activity.
Gas chromatographic analysis of HF revealed the presence of ethyl linoleate and ergosterol, compounds with known anti-inflammatory properties.
In conclusion, the nutritive compositions and significant antioxidant potential and anti-inflammatory effects of mycelia extracts of A.
rugosum have the potential to serve as a therapeutic agent or adjuvant in the management of inflammatory disorders.
American Psychological Association (APA)
Chan, Pui-Mun& Kanagasabapathy, Gowri& Tan, Yee-Shin& Sabaratnam, Vikineswary& Kuppusamy, Umah Rani. 2013. Amauroderma rugosum (Blume & T. Nees) Torrend : Nutritional Composition and Antioxidant and Potential Anti-Inflammatory Properties. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-461890
Modern Language Association (MLA)
Chan, Pui-Mun…[et al.]. Amauroderma rugosum (Blume & T. Nees) Torrend : Nutritional Composition and Antioxidant and Potential Anti-Inflammatory Properties. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-461890
American Medical Association (AMA)
Chan, Pui-Mun& Kanagasabapathy, Gowri& Tan, Yee-Shin& Sabaratnam, Vikineswary& Kuppusamy, Umah Rani. Amauroderma rugosum (Blume & T. Nees) Torrend : Nutritional Composition and Antioxidant and Potential Anti-Inflammatory Properties. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-461890
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-461890