Hemophagocytic Syndrome Associated with Immune Reconstitution Inflammatory Syndrome in a Patient with AIDS Related Burkitt’s LeukemiaLymphoma
Joint Authors
Alpay, Nilufer
Diz-Küçükkaya, Reyhan
Selcukbiricik, Fatih
Çağatay, Atahan
Kanıtez, Metin
Kapmaz, Mahir
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-27
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Highly active antiretroviral therapy (HAART) has markedly decreased human immunodeficiency virus- (HIV-) related mortality and the incidence of opportunistic infections.
The dramatic reduction in HIV-1 RNA and increase in CD4 lymphocyte count mean a recovery in immune function.
This restoration in immune function may be associated with paradoxical deterioration in subclinical opportunistic infections in some patients, a condition called immune reconstitution inflammatory syndrome (IRIS).
IRIS, a “paradoxical” inflammatory response to either previously treated or subclinical infections or noninfectious diseases, can manifest during the restoration phase of immunity hemophagocytic syndrome (HS) which is a very rare complication in patients with acquired immune deficiency syndrome (AIDS).
We describe a case of hemophagocytic syndrome associated with IRIS in a patient with AIDS related Burkitt’s leukemia/lymphoma (BL).
IRIS was probably the cause of hemophagocytosis for our patient.
Zoster infection may facilitate to IRIS.
With the increasing number of people with HIV infection and the accompanying use of HAART, much more clinical manifestations of IRIS will be experienced especially in patients given high dose chemotherapy, just like in our case.
American Psychological Association (APA)
Kanıtez, Metin& Kapmaz, Mahir& Alpay, Nilufer& Selcukbiricik, Fatih& Çağatay, Atahan& Diz-Küçükkaya, Reyhan. 2014. Hemophagocytic Syndrome Associated with Immune Reconstitution Inflammatory Syndrome in a Patient with AIDS Related Burkitt’s LeukemiaLymphoma. Case Reports in Medicine،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-462222
Modern Language Association (MLA)
Kanıtez, Metin…[et al.]. Hemophagocytic Syndrome Associated with Immune Reconstitution Inflammatory Syndrome in a Patient with AIDS Related Burkitt’s LeukemiaLymphoma. Case Reports in Medicine No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-462222
American Medical Association (AMA)
Kanıtez, Metin& Kapmaz, Mahir& Alpay, Nilufer& Selcukbiricik, Fatih& Çağatay, Atahan& Diz-Küçükkaya, Reyhan. Hemophagocytic Syndrome Associated with Immune Reconstitution Inflammatory Syndrome in a Patient with AIDS Related Burkitt’s LeukemiaLymphoma. Case Reports in Medicine. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-462222
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462222