Toward a Blended Ontology : Applying Knowledge Systems to Compare Therapeutic and Toxicological Nanoscale Domains
Joint Authors
Goldsmith, Michael-Rock
Grulke, Christopher M.
Vallero, Daniel A.
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Bionanomedicine and environmental research share need common terms and ontologies.
This study applied knowledge systems, data mining, and bibliometrics used in nano-scale ADME research from 1991 to 2011.
The prominence of nano-ADME in environmental research began to exceed the publication rate in medical research in 2006.
That trend appears to continue as a result of the growing products in commerce using nanotechnology, that is, 5-fold growth in number of countries with nanomaterials research centers.
Funding for this research virtually did not exist prior to 2002, whereas today both medical and environmental research is funded globally.
Key nanoparticle research began with pharmacology and therapeutic drug-delivery and contrasting agents, but the advances have found utility in the environmental research community.
As evidence ultrafine aerosols and aquatic colloids research increased 6-fold, indicating a new emphasis on environmental nanotoxicology.
User-directed expert elicitation from the engineering and chemical/ADME domains can be combined with appropriate Boolean logic and queries to define the corpus of nanoparticle interest.
The study combined pharmacological expertise and informatics to identify the corpus by building logical conclusions and observations.
Publication records informatics can lead to an enhanced understanding the connectivity between fields, as well as overcoming the differences in ontology between the fields.
American Psychological Association (APA)
Grulke, Christopher M.& Goldsmith, Michael-Rock& Vallero, Daniel A.. 2012. Toward a Blended Ontology : Applying Knowledge Systems to Compare Therapeutic and Toxicological Nanoscale Domains. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-462258
Modern Language Association (MLA)
Grulke, Christopher M.…[et al.]. Toward a Blended Ontology : Applying Knowledge Systems to Compare Therapeutic and Toxicological Nanoscale Domains. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-462258
American Medical Association (AMA)
Grulke, Christopher M.& Goldsmith, Michael-Rock& Vallero, Daniel A.. Toward a Blended Ontology : Applying Knowledge Systems to Compare Therapeutic and Toxicological Nanoscale Domains. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-462258
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462258