Successful Antiviral Triple Therapy in a Longstanding Refractory Hepatitis C Virus Infection with an Acute Kidney Injury
Joint Authors
Callau Monje, David
Kimmel, Martin
Alscher, Mark Dominik
Latus, Joerg
Amann, Kerstin
Braun, Niko
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
The HCV infection is a common disease with many chronically infected patients worldwide.
So far, the standard therapy of a chronic HCV infection consisted of interferon as single therapy or in combination with ribavirin.
After approval of the two protease inhibitors, boceprevir and telaprevir, the standard therapy for patients with genotype 1 changed.
In patients with acute kidney injury (AKI) these therapies are not approved and have so far not been evaluated in studies.
Case Report.
In April 2012, a 58-year-old female was admitted due to a cryoglobulin-positive chronic HCV infection which had been treated with interferon and ribavirin.
Currently, the patient was admitted because of severe complications with an acute kidney injury.
We treated our patient successfully with a boceprevir based triple therapy.
Conclusion.
Limited data suggests that a therapy with ribavirin in patients with AKI seems to be safe under close monitoring.
Our patient was treated successfully with a protease inhibitor based triple therapy.
Nevertheless, it is necessary to plan an interventional study to evaluate the exact risk-benefit profile of triple therapy regimens in patients with AKI and hepatitis C.
American Psychological Association (APA)
Callau Monje, David& Braun, Niko& Latus, Joerg& Amann, Kerstin& Alscher, Mark Dominik& Kimmel, Martin. 2014. Successful Antiviral Triple Therapy in a Longstanding Refractory Hepatitis C Virus Infection with an Acute Kidney Injury. Case Reports in Nephrology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-462305
Modern Language Association (MLA)
Callau Monje, David…[et al.]. Successful Antiviral Triple Therapy in a Longstanding Refractory Hepatitis C Virus Infection with an Acute Kidney Injury. Case Reports in Nephrology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-462305
American Medical Association (AMA)
Callau Monje, David& Braun, Niko& Latus, Joerg& Amann, Kerstin& Alscher, Mark Dominik& Kimmel, Martin. Successful Antiviral Triple Therapy in a Longstanding Refractory Hepatitis C Virus Infection with an Acute Kidney Injury. Case Reports in Nephrology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-462305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462305