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Fibrous Variant of Hashimoto’s Thyroiditis as a Diagnostic Pitfall in Thyroid Pathology
Joint Authors
Sapere, P.
Faggiano, A.
Colao, A.
Coluccino, V.
Iannaci, G.
Luise, R.
Spiezia, S.
Ronchi, A.
Marotta, V.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Fibrous variant of Hashimoto’s thyroiditis is a rare condition occurring in about 10% cases, mainly middle age people.
It is characterized by an extensive fibrous proliferation without extension into the surrounding structures.
A 55-year-old female was referred to our department for an unexplained onset of cervical discomfort.
She presented a voluminous goiter of hard consistence, dyspnea and dysphagia.
Given the compressive symptoms and the non-diagnostic result of the biopsy, a total thyroidectomy was performed.
Microscopically the thyroid parenchyma was characterized by broad bands of fibrosis with severe atrophy of thyroid follicles and lymphocytic inflammatory infiltrate distributed within and around the lobules.
In view of the morphological and immunohistochemical findings, a diagnosis of HTFV was made.
The fibrosclerotic process is the key feature of several thyroid diseases so that the clinician and the pathologist have to consider that many diagnostic pitfalls can occur in this field.
The differential diagnosis between HTFV and RD is sometimes arduous due to the partial clinical and morphological overlapping and to the poor efficacy of conventional cytology as well as pre-surgical biopsy.
Considering these features, histological examination is mostly mandatory.
American Psychological Association (APA)
Iannaci, G.& Luise, R.& Sapere, P.& Coluccino, V.& Ronchi, A.& Faggiano, A.…[et al.]. 2013. Fibrous Variant of Hashimoto’s Thyroiditis as a Diagnostic Pitfall in Thyroid Pathology. Case Reports in Endocrinology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-462312
Modern Language Association (MLA)
Iannaci, G.…[et al.]. Fibrous Variant of Hashimoto’s Thyroiditis as a Diagnostic Pitfall in Thyroid Pathology. Case Reports in Endocrinology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-462312
American Medical Association (AMA)
Iannaci, G.& Luise, R.& Sapere, P.& Coluccino, V.& Ronchi, A.& Faggiano, A.…[et al.]. Fibrous Variant of Hashimoto’s Thyroiditis as a Diagnostic Pitfall in Thyroid Pathology. Case Reports in Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-462312
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462312