![](/images/graphics-bg.png)
Which Approach Is More Effective in the Selection of Plants with Antimicrobial Activity?
Joint Authors
Coutinho, Felipe Neves
Pisciottano, Maria Nelly Caetano
Saraiva, Antonio Marcos
Castro, Ricardo Henrique Acre
Silva, Ana Carolina Oliveira
de Amorim, Elba Lúcia Cavalcanti
Albuquerque, Ulysses Paulino de
Santana, Elidiane Fonseca
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The development of the present study was based on selections using random, direct ethnopharmacological, and indirect ethnopharmacological approaches, aiming to evaluate which method is the best for bioprospecting new antimicrobial plant drugs.
A crude extract of 53 species of herbaceous plants collected in the semiarid region of Northeast Brazil was tested against 11 microorganisms.
Well-agar diffusion and minimum inhibitory concentration (MIC) techniques were used.
Ten extracts from direct, six from random, and three from indirect ethnopharmacological selections exhibited activities that ranged from weak to very active against the organisms tested.
The strain most susceptible to the evaluated extracts was Staphylococcus aureus.
The MIC analysis revealed the best result for the direct ethnopharmacological approach, considering that some species yielded extracts classified as active or moderately active (MICs between 250 and 1000 µg/mL).
Furthermore, one species from this approach inhibited the growth of the three Candida strains.
Thus, it was concluded that the direct ethnopharmacological approach is the most effective when selecting species for bioprospecting new plant drugs with antimicrobial activities.
American Psychological Association (APA)
Silva, Ana Carolina Oliveira& Santana, Elidiane Fonseca& Saraiva, Antonio Marcos& Coutinho, Felipe Neves& Castro, Ricardo Henrique Acre& Pisciottano, Maria Nelly Caetano…[et al.]. 2013. Which Approach Is More Effective in the Selection of Plants with Antimicrobial Activity?. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-462321
Modern Language Association (MLA)
Silva, Ana Carolina Oliveira…[et al.]. Which Approach Is More Effective in the Selection of Plants with Antimicrobial Activity?. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-462321
American Medical Association (AMA)
Silva, Ana Carolina Oliveira& Santana, Elidiane Fonseca& Saraiva, Antonio Marcos& Coutinho, Felipe Neves& Castro, Ricardo Henrique Acre& Pisciottano, Maria Nelly Caetano…[et al.]. Which Approach Is More Effective in the Selection of Plants with Antimicrobial Activity?. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-462321
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462321