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Efficacy of Corticosteroids Alone in the Eradication of Factor VIII Inhibitor in an Old Female with Idiopathic Acquired Haemophilia A : Description of a Case
Joint Authors
Girelli, Francesco
Gardelli, Lucia
Bondi, Gabriele
Bagioni, Franco
Camporesi, Claudio
Mazzeo, Vincenzo
Biasoli, Chiara
Nizzoli, Maurizio
Bassi, Bruna
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-29
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Acquired haemophilia A (AHA) is a rare and serious disorder mainly affecting elderly patients.
It is caused by the production of autoantibodies directed against coagulation factors; patients present with spontaneous bleeding, potentially fatal, in the absence of familial or personal history.
Autoimmune disorders, infections, solid and hematologic tumors, and drugs are predisposing factors, but up to 50 percent of cases remain unexplained.
The diagnosis of AHA is confirmed by specific laboratory tests; and the therapy is a clinical challenge, due to the fact that older patients are often affected by comorbidities.
By passing agents may be used when persistent bleeding or haemodynamic instability is observed; corticosteroids, alone or with immunosuppressive therapy, are necessary to inhibit the production of the autoantibodies.
We describe a case in which steroids in monotherapy successfully, safely, and persistently inhibited the production of anti-Factor VIII antibodies, in an old patient admitted after rheumatologic consult.
American Psychological Association (APA)
Girelli, Francesco& Biasoli, Chiara& Bassi, Bruna& Bagioni, Franco& Bondi, Gabriele& Camporesi, Claudio…[et al.]. 2012. Efficacy of Corticosteroids Alone in the Eradication of Factor VIII Inhibitor in an Old Female with Idiopathic Acquired Haemophilia A : Description of a Case. Case Reports in Rheumatology،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-462482
Modern Language Association (MLA)
Girelli, Francesco…[et al.]. Efficacy of Corticosteroids Alone in the Eradication of Factor VIII Inhibitor in an Old Female with Idiopathic Acquired Haemophilia A : Description of a Case. Case Reports in Rheumatology No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-462482
American Medical Association (AMA)
Girelli, Francesco& Biasoli, Chiara& Bassi, Bruna& Bagioni, Franco& Bondi, Gabriele& Camporesi, Claudio…[et al.]. Efficacy of Corticosteroids Alone in the Eradication of Factor VIII Inhibitor in an Old Female with Idiopathic Acquired Haemophilia A : Description of a Case. Case Reports in Rheumatology. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-462482
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462482