Persistent CSF Rhinorrhoea, Pneumocephalus, and Recurrent Meningitis Following Misdiagnosis of Olfactory Neuroblastoma
Joint Authors
Pobereskin, Louis
Hilton, David A.
Khalil, Hisham
Mukonoweshuro, William
Barua, Neil
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 41-year-old female patient was admitted with streptococcal meningitis on a background of 5-month history of CSF rhinorrhoea.
Imaging revealed an extensive skull base lesion involving the sphenoid and ethmoid sinuses, the pituitary fossa with suprasellar extension and bony destruction.
Histological examination of an endonasal transethmoidal biopsy suggested a diagnosis of olfactory neuroblastoma.
A profuse CSF leak occurred and the patient developed coliform meningitis.
A second endonasal endoscopic biopsy was undertaken which demonstrated the tumour to be a prolactinoma.
Following endonasal repair of the CSF leak and lumbar drainage, she developed profound pneumocephalus.
The patient underwent three further unsuccessful CSF leak repairs.
Definitive control of the CSF leak was finally achieved through a transcranial approach with prolonged lumbar drainage.
This case illustrates some of the potentially devastating complications which can occur as a consequence of complex skull base lesions.
A multidisciplinary approach may be required to successfully manage such cases.
American Psychological Association (APA)
Barua, Neil& Hilton, David A.& Mukonoweshuro, William& Khalil, Hisham& Pobereskin, Louis. 2010. Persistent CSF Rhinorrhoea, Pneumocephalus, and Recurrent Meningitis Following Misdiagnosis of Olfactory Neuroblastoma. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-462526
Modern Language Association (MLA)
Barua, Neil…[et al.]. Persistent CSF Rhinorrhoea, Pneumocephalus, and Recurrent Meningitis Following Misdiagnosis of Olfactory Neuroblastoma. Case Reports in Medicine No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-462526
American Medical Association (AMA)
Barua, Neil& Hilton, David A.& Mukonoweshuro, William& Khalil, Hisham& Pobereskin, Louis. Persistent CSF Rhinorrhoea, Pneumocephalus, and Recurrent Meningitis Following Misdiagnosis of Olfactory Neuroblastoma. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-462526
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462526