Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function : The Multiethnic Study of Atherosclerosis
Joint Authors
Lima, João
Tsai, Michael Y.
Steffen, Lyn M.
Siscovick, David S.
Lemaitre, Rozenn N.
Hundley, W. Gregory
Anderson, Jennifer S.
Herrington, David M.
Nettleton, Jennifer A.
Prince, Martin R.
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
The association between plasma omega-6 fatty acids and cardiovascular disease (CVD) is unclear, and discrepancy remains concerning the cardiovascular benefit of the omega-3 fatty acid alpha-linolenic acid.
Methods.
Associations of plasma phospholipid fatty acid levels (arachidonic acid, linoleic acid, eicosapentaenoic acid, docosahexaenoic acid (DHA), and alpha-linolenic acid) with cardiac magnetic resonance imaging measures of left ventricular (LV) mass, LV volume, ejection fraction, stroke volume, and aortic distensibility were investigated in 1,274 adults.
Results.
Results of multivariate analysis showed no statistically significant associations of plasma omega-6 or omega-3 levels with cardiac magnetic resonance imaging measures.
Stratification by gender revealed a positive association between DHA and LV mass in women (β=1.89, P=0.02; P interaction = 0.003) and a trend for a positive association between DHA and ejection fraction in men (β=0.009, P=0.05; P interaction = 0.03).
Conclusion.
Additional research is warranted to clarify the effects of plasma DHA on cardiac structure and function in women versus men.
American Psychological Association (APA)
Anderson, Jennifer S.& Nettleton, Jennifer A.& Hundley, W. Gregory& Tsai, Michael Y.& Steffen, Lyn M.& Lemaitre, Rozenn N.…[et al.]. 2011. Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function : The Multiethnic Study of Atherosclerosis. Journal of Nutrition and Metabolism،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-462791
Modern Language Association (MLA)
Anderson, Jennifer S.…[et al.]. Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function : The Multiethnic Study of Atherosclerosis. Journal of Nutrition and Metabolism No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-462791
American Medical Association (AMA)
Anderson, Jennifer S.& Nettleton, Jennifer A.& Hundley, W. Gregory& Tsai, Michael Y.& Steffen, Lyn M.& Lemaitre, Rozenn N.…[et al.]. Associations of Plasma Phospholipid Omega-6 and Omega-3 Polyunsaturated Fatty Acid Levels and MRI Measures of Cardiovascular Structure and Function : The Multiethnic Study of Atherosclerosis. Journal of Nutrition and Metabolism. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-462791
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462791