Mesotherapy versus Systemic Therapy in the Treatment of Acute Low Back Pain : A Randomized Trial
Joint Authors
Marangio, Emilio
Coruzzi, Gabriella
Costantino, Cosimo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Pharmacological therapy of back pain with analgesics and anti-inflammatory drugs is frequently associated with adverse effects, particularly in the elderly.
Aim of this study was to compare mesotherapic versus conventional systemic administration of nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids in patients with acute low back pain.
Eighty-four patients were randomized to receive anti-inflammatory therapy according to the following protocols: (a) mesotherapy group received the 1st and 4th day 2% lidocaine (1 mL) + ketoprofen 160 mg (1 mL) + methylprednisolone 40 mg (1 mL), then on 7th, 10th, and 13th day, 2% lidocaine (1 mL) + ketoprofen 160 mg (1 mL) + methylprednisolone 20 mg (1 mL) (b) conventional therapy group received ketoprofen 80 mg × 2/die and esomeprazole 20 mg/die orally for 12 days, methylprednisolone 40 mg/die intramuscularly for 4 days, followed by methylprednisolone 20 mg/die for 3 days, and thereafter, methylprednisolone 20 mg/die at alternate days.
Pain intensity and functional disability were assessed at baseline (T0), at the end of treatment (T1), and 6 months thereafter (T2) by using visual analogic scale (VAS) and Roland-Morris disability questionnaire (RMDQ).
In both groups, VAS and RMDQ values were significantly reduced at the end of drug treatment and after 6 months, in comparison with baseline.
No significant differences were found between the two groups.
This suggests that mesotherapy may be a valid alternative to conventional therapy in the treatment of acute low back pain with corticosteroids and NSAIDs.
American Psychological Association (APA)
Costantino, Cosimo& Marangio, Emilio& Coruzzi, Gabriella. 2010. Mesotherapy versus Systemic Therapy in the Treatment of Acute Low Back Pain : A Randomized Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-462979
Modern Language Association (MLA)
Costantino, Cosimo…[et al.]. Mesotherapy versus Systemic Therapy in the Treatment of Acute Low Back Pain : A Randomized Trial. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-462979
American Medical Association (AMA)
Costantino, Cosimo& Marangio, Emilio& Coruzzi, Gabriella. Mesotherapy versus Systemic Therapy in the Treatment of Acute Low Back Pain : A Randomized Trial. Evidence-Based Complementary and Alternative Medicine. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-462979
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-462979