DNA Methylation Pattern as Important Epigenetic Criterion in Cancer
Joint Authors
Ghavifekr Fakhr, Mehrdad
Farshdousti Hagh, Majid
Baradaran, Behzad
Shanehbandi, Dariush
Source
Genetics Research International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Epigenetic modifications can affect the long-term gene expression without any change in nucleotide sequence of the DNA.
Epigenetic processes intervene in the cell differentiation, chromatin structure, and activity of genes since the embryonic period.
However, disorders in genes’ epigenetic pattern can affect the mechanisms such as cell division, apoptosis, and response to the environmental stimuli which may lead to the incidence of different diseases and cancers.
Since epigenetic changes may return to their natural state, they could be used as important targets in the treatment of cancer and similar malignancies.
The aim of this review is to assess the epigenetic changes in normal and cancerous cells, the causative factors, and epigenetic therapies and treatments.
American Psychological Association (APA)
Ghavifekr Fakhr, Mehrdad& Farshdousti Hagh, Majid& Shanehbandi, Dariush& Baradaran, Behzad. 2013. DNA Methylation Pattern as Important Epigenetic Criterion in Cancer. Genetics Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-463020
Modern Language Association (MLA)
Ghavifekr Fakhr, Mehrdad…[et al.]. DNA Methylation Pattern as Important Epigenetic Criterion in Cancer. Genetics Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-463020
American Medical Association (AMA)
Ghavifekr Fakhr, Mehrdad& Farshdousti Hagh, Majid& Shanehbandi, Dariush& Baradaran, Behzad. DNA Methylation Pattern as Important Epigenetic Criterion in Cancer. Genetics Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-463020
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463020