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Tyrosine Kinase Signaling in Kidney Glomerular Podocytes
Joint Authors
Harita, Yutaka
Kanda, Shoichiro
Hattori, Seisuke
Source
Journal of Signal Transduction
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
During the last decade, several key molecules have been identified as essential components for the filtration barrier function of kidney glomerular podocytes.
Mutations in genes encoding these molecules severely impair the podocyte architecture in the affected patients, leading to the development of proteinuria.
Extensive investigations have been performed on the function of these molecules, which highlights the importance of tyrosine kinase signaling in the podocytes.
An Src family tyrosine kinase, Fyn, plays a major role in this signaling pathway.
Here, we review the current understanding of this important signal transduction system and its role in the development and the maintenance of podocytes.
American Psychological Association (APA)
Hattori, Seisuke& Kanda, Shoichiro& Harita, Yutaka. 2011. Tyrosine Kinase Signaling in Kidney Glomerular Podocytes. Journal of Signal Transduction،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-463046
Modern Language Association (MLA)
Hattori, Seisuke…[et al.]. Tyrosine Kinase Signaling in Kidney Glomerular Podocytes. Journal of Signal Transduction No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-463046
American Medical Association (AMA)
Hattori, Seisuke& Kanda, Shoichiro& Harita, Yutaka. Tyrosine Kinase Signaling in Kidney Glomerular Podocytes. Journal of Signal Transduction. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-463046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463046