Expression of Potential Regulatory Genes in Abdominal Adipose Tissue of Broiler Chickens during Early Development
Joint Authors
Bohannon-Stewart, Ann
Donkor, Joseph
Kimathi, Boniface
Subramanya, Sri Harsha K. V.
Payne, Ashley
Ivy, Michael
Chen, Fur-Chi
Tyus, James
Wang, Xiaofei
Kelley, Gary
Hui, Dafeng
Byers, Shannon
Darris, Carl
Nahashon, Samuel
Source
Genetics Research International
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The identities of genes that underlie population variation in adipose tissue development in farm animals are poorly understood.
Previous studies in our laboratory have suggested that increased fat tissue involves the expression modulation of an array of genes in broiler chickens.
Of special interest are eight genes, FGFR3, EPHB2, IGFBP2, GREM1, TNC, COL3A1, ACBD7, and SCD.
To understand their expression regulation and response to dietary manipulation, we investigated their mRNA levels after dietary manipulation during early development.
Chickens were fed either a recommended standard or a high caloric diet from hatch to eight weeks of age (WOA).
The high caloric diet markedly affected bodyweight of the broiler birds.
mRNA levels of the eight genes in the abdominal adipose tissue were assayed at 2, 4, 6, and 8 WOA using RT-qPCR.
Results indicate that (1) FGFR3 mRNA level was affected significantly by diet, age, and diet:age interaction; (2) COL3A mRNA level was repressed by high caloric diet; (3) mRNA levels of EPHB2, ACBD7, and SCD were affected by age; (4) mRNA level of TNC was modulated by age:diet interaction; (5) changes in GREM1 and IGFBP2 mRNA levels were not statistically different.
American Psychological Association (APA)
Bohannon-Stewart, Ann& Kelley, Gary& Kimathi, Boniface& Subramanya, Sri Harsha K. V.& Donkor, Joseph& Darris, Carl…[et al.]. 2014. Expression of Potential Regulatory Genes in Abdominal Adipose Tissue of Broiler Chickens during Early Development. Genetics Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-463090
Modern Language Association (MLA)
Bohannon-Stewart, Ann…[et al.]. Expression of Potential Regulatory Genes in Abdominal Adipose Tissue of Broiler Chickens during Early Development. Genetics Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-463090
American Medical Association (AMA)
Bohannon-Stewart, Ann& Kelley, Gary& Kimathi, Boniface& Subramanya, Sri Harsha K. V.& Donkor, Joseph& Darris, Carl…[et al.]. Expression of Potential Regulatory Genes in Abdominal Adipose Tissue of Broiler Chickens during Early Development. Genetics Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-463090
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463090