Modulation of PPAR-γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases
Joint Authors
López-Roa, Rocío Ivette
Rojas-Mayorquín, Argelia E.
Márquez-Aguirre, A. L.
Ortuño-Sahagún, Daniel
Quintero-Fabián, S.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-28
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
A direct correlation between adequate nutrition and health is a universally accepted truth.
The Western lifestyle, with a high intake of simple sugars, saturated fat, and physical inactivity, promotes pathologic conditions.
The main adverse consequences range from cardiovascular disease, type 2 diabetes, and metabolic syndrome to several cancers.
Dietary components influence tissue homeostasis in multiple ways and many different functional foods have been associated with various health benefits when consumed.
Natural products are an important and promising source for drug discovery.
Many anti-inflammatory natural products activate peroxisome proliferator-activated receptors (PPAR); therefore, compounds that activate or modulate PPAR-gamma (PPAR-γ) may help to fight all of these pathological conditions.
Consequently, the discovery and optimization of novel PPAR-γ agonists and modulators that would display reduced side effects is of great interest.
In this paper, we present some of the main naturally derived products studied that exert an influence on metabolism through the activation or modulation of PPAR-γ, and we also present PPAR-γ-related diseases that can be complementarily treated with nutraceutics from functional foods.
American Psychological Association (APA)
Ortuño-Sahagún, Daniel& Márquez-Aguirre, A. L.& Quintero-Fabián, S.& López-Roa, Rocío Ivette& Rojas-Mayorquín, Argelia E.. 2012. Modulation of PPAR-γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases. PPAR Research،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-463118
Modern Language Association (MLA)
Ortuño-Sahagún, Daniel…[et al.]. Modulation of PPAR-γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases. PPAR Research No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-463118
American Medical Association (AMA)
Ortuño-Sahagún, Daniel& Márquez-Aguirre, A. L.& Quintero-Fabián, S.& López-Roa, Rocío Ivette& Rojas-Mayorquín, Argelia E.. Modulation of PPAR-γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases. PPAR Research. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-463118
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463118