Cancer Stem Cell Markers in Head and Neck Squamous Cell Carcinoma
Joint Authors
Farah, Camile S.
Pitty, Luke P.
Major, Aidan G.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-03
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Head and neck squamous cell carcinoma (HNSCC) is one of the world’s top ten most common cancers.
Current survival rates are poor with only 50% of patients expected to survive five years after diagnosis.
The poor survival rate of HNSCC is partly attributable to the tendency for diagnosis at the late stage of the disease.
One of the reasons for treatment failure is thought to be related to the presence of a subpopulation of cells within the tumour called cancer stem cells (CSCs).
CSCs display stem cell-like characteristics that impart resistance to conventional treatment modalities and promote tumour initiation, progression, and metastasis.
Specific markers for this population have been investigated in the hope of developing a deeper understanding of their role in the pathogenesis of HNSCC and elucidating novel therapeutic strategies.
American Psychological Association (APA)
Major, Aidan G.& Pitty, Luke P.& Farah, Camile S.. 2013. Cancer Stem Cell Markers in Head and Neck Squamous Cell Carcinoma. Stem Cells International،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-463191
Modern Language Association (MLA)
Major, Aidan G.…[et al.]. Cancer Stem Cell Markers in Head and Neck Squamous Cell Carcinoma. Stem Cells International No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-463191
American Medical Association (AMA)
Major, Aidan G.& Pitty, Luke P.& Farah, Camile S.. Cancer Stem Cell Markers in Head and Neck Squamous Cell Carcinoma. Stem Cells International. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-463191
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463191