Oxidative Stress and Its Clinical Applications in Dementia
Author
Source
Journal of Neurodegenerative Diseases
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-30
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Dementia is a complex disorder that mostly affects the elderly and represents a significant and growing public health burden in the world.
Alzheimer’s disease (AD)- associated dementia and dementia with Lewy bodies (DLB) are the most common forms of dementia, in which oxidative stress is significantly involved.
Oxidative stress mechanisms may have clinical applications, that is, providing information for potential biomarkers.
Thus brain-rich peptides with an antioxidant property, such as CART (cocaine- and amphetamine-regulated transcript), may be promising new markers.
This paper summarizes the progress in research regarding oxidative stress in dementia with a focus on potential biomarkers in the cerebrospinal fluid (CSF) in the main forms of dementia.
Other central and peripheral biomarkers, especially those considered oxidative stress related, are also discussed.
This paper aims to provide information to improve current understanding of the pathogenesis and progression of dementia.
It also offers insight into the differential diagnosis of AD and DLB.
American Psychological Association (APA)
Mao, Peizhong. 2012. Oxidative Stress and Its Clinical Applications in Dementia. Journal of Neurodegenerative Diseases،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-463229
Modern Language Association (MLA)
Mao, Peizhong. Oxidative Stress and Its Clinical Applications in Dementia. Journal of Neurodegenerative Diseases No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-463229
American Medical Association (AMA)
Mao, Peizhong. Oxidative Stress and Its Clinical Applications in Dementia. Journal of Neurodegenerative Diseases. 2012. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-463229
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463229