Myeloid Neoplasias : What Molecular Analyses Are Telling Us
Joint Authors
Renault, Ilana Zalcberg
Lipkin, Marina V.
Gutiyama, Luciana M.
Coutinho, Diego F.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
In the last decades, cytogenetic and molecular characterizations of hematological disorders at diagnosis and followup have been most valuable for guiding therapeutic decisions and prognosis.
Genetic and epigenetic alterations detected by different procedures have been associated to different cancer types and are considered important indicators for disease classification, differential diagnosis, prognosis, response, and individualization of therapy.
The search for new biomarkers has been revolutionized by high-throughput technologies.
At this point, it seems that we have overcome technological barriers, but we are still far from sorting the biological puzzle.
Evidence based on translational research is required for validating novel genetic and epigenetic markers for routine clinical practice.
We herein discuss the importance of genetic abnormalities and their molecular pathways in acute myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms.
We also discuss how novel genomic abnormalities may interact and reassess concepts and classifications of myeloid neoplasias.
American Psychological Association (APA)
Gutiyama, Luciana M.& Coutinho, Diego F.& Lipkin, Marina V.& Renault, Ilana Zalcberg. 2012. Myeloid Neoplasias : What Molecular Analyses Are Telling Us. ISRN Oncology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463341
Modern Language Association (MLA)
Gutiyama, Luciana M.…[et al.]. Myeloid Neoplasias : What Molecular Analyses Are Telling Us. ISRN Oncology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-463341
American Medical Association (AMA)
Gutiyama, Luciana M.& Coutinho, Diego F.& Lipkin, Marina V.& Renault, Ilana Zalcberg. Myeloid Neoplasias : What Molecular Analyses Are Telling Us. ISRN Oncology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463341
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463341