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Detection of Hepatitis C Virus Coinfection in Patients with Dengue Diagnosis
Joint Authors
Cetina-Trejo, Rosa Carmina
Salazar, Ma. Isabel
Puerto, Fernando I.
Rivero-Cárdenas, Nubia
Farfán-Ale, José Arturo
Talavera-Aguilar, Lourdes
Castro-Mussot, María Eugenia
Machain-Williams, Carlos
Carrillo-Navarrete, Jaquelin
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Coinfection produced by dengue virus (DENV) and hepatitis C virus (HCV) is a serious problem of public health in Mexico, as they both circulate in tropical zones and may lead to masking or complicating symptoms.
In this research, we detected active coinfected patients by HCV residing in the endemic city of Mérida, Yucatán, Mexico, with positive diagnosis to dengue during the acute phase.
We performed a retrospective analysis of 240 serum samples from dengue patients.
The IgM-ELISA serological test was used for dengue diagnosis, as well as viral isolation to confirm infection.
DENV and HCV were detected by RT-PCR.
Thus, 31 (12.9%) samples showed DENV-HCV coinfection, but interestingly the highest frequency of coinfection cases was found in male patients presenting hemorrhagic dengue in 19/31 (61.29%), with a predominance of 12 : 7 in males.
Firstly, coinfection of DENV-HCV in Mérida, Mexico, was detected in young dengue patients, between 11 and 20 years old (38.7%), followed by those between 21 and 30 years old (32%); only 16.13% were between 0 and 10 years of age.
Diagnosis of HCV infection in patients with dengue is highly recommended in order to establish potential risk in clinical manifestations as well as dictate patients' special care.
American Psychological Association (APA)
Machain-Williams, Carlos& Talavera-Aguilar, Lourdes& Cetina-Trejo, Rosa Carmina& Carrillo-Navarrete, Jaquelin& Rivero-Cárdenas, Nubia& Salazar, Ma. Isabel…[et al.]. 2014. Detection of Hepatitis C Virus Coinfection in Patients with Dengue Diagnosis. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-463346
Modern Language Association (MLA)
Machain-Williams, Carlos…[et al.]. Detection of Hepatitis C Virus Coinfection in Patients with Dengue Diagnosis. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-463346
American Medical Association (AMA)
Machain-Williams, Carlos& Talavera-Aguilar, Lourdes& Cetina-Trejo, Rosa Carmina& Carrillo-Navarrete, Jaquelin& Rivero-Cárdenas, Nubia& Salazar, Ma. Isabel…[et al.]. Detection of Hepatitis C Virus Coinfection in Patients with Dengue Diagnosis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-463346
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463346