Can We Find Better Bronchodilators to Relieve Asthma Symptoms?
Joint Authors
Gallos, George
Emala, Charles W.
Yim, Peter D.
Townsend, Elizabeth A.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Bronchodilators are the first line therapy during acute asthmatic exacerbations to reverse airway obstruction primarily by relaxing airway smooth muscle.
Only three categories of bronchodilators exist in clinical practice: β-adrenergic agonists, anticholinergics, and methylxanthines.
Each of these categories have specific drugs dating back to the early 20th century, raising the question of whether or not we can find better bronchodilators.
While caffeine, theophylline, atropine, and epinephrine were the first generations of therapeutics in each of these drug classes, there is no question that improvements have been made in the bronchodilators in each of these classes.
In the following editorial, we will briefly describe new classes of potential bronchodilators including: novel PDE inhibitors, natural phytotherapeutics, bitter taste receptor ligands, and chloride channel modulators, which have the potential to be used alone or in combination with existing bronchodilators to reverse acute airway obstruction in the future.
American Psychological Association (APA)
Townsend, Elizabeth A.& Yim, Peter D.& Gallos, George& Emala, Charles W.. 2012. Can We Find Better Bronchodilators to Relieve Asthma Symptoms?. Journal of Allergy،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-463411
Modern Language Association (MLA)
Townsend, Elizabeth A.…[et al.]. Can We Find Better Bronchodilators to Relieve Asthma Symptoms?. Journal of Allergy No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-463411
American Medical Association (AMA)
Townsend, Elizabeth A.& Yim, Peter D.& Gallos, George& Emala, Charles W.. Can We Find Better Bronchodilators to Relieve Asthma Symptoms?. Journal of Allergy. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-463411
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463411