![](/images/graphics-bg.png)
Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density?
Joint Authors
Taylor, Valerie H.
Chau, Kim
Atkinson, Stephanie A.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Osteoporosis is a chronic disease that can significantly impact numerous aspects of health and wellness.
The individual consequences of osteoporosis can be devastating, often resulting in substantial loss of independence and sometimes death.
One of the few illnesses with greater disease burden than low bone mineral density (BMD) is major depressive disorder (MDD).
Both depression and antidepressant use have been identified as secondary causes of osteoporosis.
The objective of this paper is to review and summarize the current findings on the relationship between antidepressant use and BMD.
Methods.
Relevant sources were identified from the Pubmed and MEDLINE databases, citing articles from the first relevant publication to September 1st, 2010.
Results.
2001 articles initially met the search criteria, and 35 studies were thoroughly reviewed for evidence of an association between SSRI use and BMD, and 8 clinical studies were detailed and summarized in this paper.
Conclusions.
Current findings suggest a link between mental illness and osteoporosis that is of clinical relevance.
Additional longitudinal studies and further research on possible mechanisms surrounding the association between SSRI use on bone metabolism need to be conducted.
Treatment algorithms need to recognize this association to ensure that vulnerable populations are screened.
American Psychological Association (APA)
Chau, Kim& Atkinson, Stephanie A.& Taylor, Valerie H.. 2012. Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density?. Journal of Osteoporosis،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463419
Modern Language Association (MLA)
Chau, Kim…[et al.]. Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density?. Journal of Osteoporosis No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-463419
American Medical Association (AMA)
Chau, Kim& Atkinson, Stephanie A.& Taylor, Valerie H.. Are Selective Serotonin Reuptake Inhibitors a Secondary Cause of Low Bone Density?. Journal of Osteoporosis. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463419
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463419