Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts
Joint Authors
Cardoso, Cássia Regina Primila
da Silva Moura, Adriana Candido
Vilegas, Wagner
Colus, Ilce Mara Syllos
Calvo, Tamara Regina
Varanda, Eliana Aparecida
dos Santos, Lourdes Campaner
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Indigofera truxillensis and I.
suffruticosa, are used as a source of indigo dye and to treat several diseases.
The mutagenic activity of the methanolic extracts from aerial parts, glycerolipid, flavonoid and alkaloid fractions of the extract were evaluated by means of Salmonella/microsome assays using TA100, TA98, TA102 and TA97a strains.
The methanolic extract of I.
truxillensis showed mutagenic activity in the TA98 strain without S9 while glycerolipid fraction was devoid of activity.
The flavonoid and alkaloid fractions of both plants showed mutagenicity.
Chemical analysis of flavonoid fractions of I.
truxillensis and I.
suffruticosa resulted in the identification of kaempferol, quercetin and their derivatives.
The alkaloid fraction of both the species contained indigo and indirubin and indigo was found mainly responsible for the mutagenic activity.
American Psychological Association (APA)
Calvo, Tamara Regina& Cardoso, Cássia Regina Primila& da Silva Moura, Adriana Candido& dos Santos, Lourdes Campaner& Colus, Ilce Mara Syllos& Vilegas, Wagner…[et al.]. 2011. Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-463439
Modern Language Association (MLA)
Calvo, Tamara Regina…[et al.]. Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-463439
American Medical Association (AMA)
Calvo, Tamara Regina& Cardoso, Cássia Regina Primila& da Silva Moura, Adriana Candido& dos Santos, Lourdes Campaner& Colus, Ilce Mara Syllos& Vilegas, Wagner…[et al.]. Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-463439
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463439
