Intake of Grains and Dietary Fiber and Prostate Cancer Aggressiveness by Race
Joint Authors
Zhang, Hongmei
Su, L. Joseph
Arab, Lenore
Mohler, James L.
Steck, Susan E.
Tabung, Fred
Bensen, Jeannette T.
Fontham, Elizabeth T. H.
Hébert, James R.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To examine the associations among intake of refined grains, whole grains and dietary fiber and aggressiveness of prostate cancer in African Americans (AA, n=930) and European Americans (EA, n=993) in a population-based, case-only study (The North Carolina-Louisiana Prostate Cancer Project, PCaP).
Methods.
Prostate cancer aggressiveness was categorized as high, intermediate or low based on Gleason grade, PSA level and clinical stage.
Dietary intake was assessed utilizing the NCI Diet History Questionnaire.
Logistic regression (comparing high to intermediate/low aggressive cancers) and polytomous regression with adjustment for potential confounders were used to determine odds of high prostate cancer aggressiveness with intake of refined grains, whole grains and dietary fiber from all sources.
Results.
An inverse association with aggressive prostate cancer was observed in the 2nd and 3rd tertiles of total fiber intake (OR = 0.70; 95% CI, 0.50–0.97 and OR = 0.61; 95% CI, 0.40–0.93, resp.) as compared to the lowest tertile of intake.
In the race-stratified analyses, inverse associations were observed in the 3rd tertile of total fiber intake for EA (OR = 0.44; 95% CI, 0.23–0.87) and the 2nd tertile of intake for AA (OR = 0.57; 95% CI, 0.35–0.95).
Conclusions.
Dietary fiber intake was inversely associated with aggressive prostate cancer among both AA and EA men.
American Psychological Association (APA)
Tabung, Fred& Steck, Susan E.& Su, L. Joseph& Mohler, James L.& Fontham, Elizabeth T. H.& Bensen, Jeannette T.…[et al.]. 2012. Intake of Grains and Dietary Fiber and Prostate Cancer Aggressiveness by Race. Prostate Cancer،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-463442
Modern Language Association (MLA)
Tabung, Fred…[et al.]. Intake of Grains and Dietary Fiber and Prostate Cancer Aggressiveness by Race. Prostate Cancer No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-463442
American Medical Association (AMA)
Tabung, Fred& Steck, Susan E.& Su, L. Joseph& Mohler, James L.& Fontham, Elizabeth T. H.& Bensen, Jeannette T.…[et al.]. Intake of Grains and Dietary Fiber and Prostate Cancer Aggressiveness by Race. Prostate Cancer. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-463442
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463442