Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background
Joint Authors
Faitelson, A. V.
Dubrovin, G. M.
Gudyrev, O. S.
Pokrovskiy, Mihail V.
Rajkumar, D. S. R.
Ivanov, A. V.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
In the experiment on the white Wistar female rats (222 animals), the osteoprotective effect of enalapril and losartan was studied on experimental models of osteoporosis and osteoporotic fractures.
It was revealed that in rats after ovariectomy, the endothelial dysfunction of microcirculation vessels of osteal tissue develops, resulting in occurrence of osteoporosis and delay of consolidation of experimental fractures.
Enalapril and losartan prevented the reduction of microcirculation in bone, which was reflected in slowing the thinning of bone trabeculae and in preventing the occurrence of these microfractures, as well as increasing quality of experimental fractures healing.
American Psychological Association (APA)
Rajkumar, D. S. R.& Faitelson, A. V.& Gudyrev, O. S.& Dubrovin, G. M.& Pokrovskiy, Mihail V.& Ivanov, A. V.. 2013. Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background. Journal of Osteoporosis،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-463664
Modern Language Association (MLA)
Rajkumar, D. S. R.…[et al.]. Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background. Journal of Osteoporosis No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-463664
American Medical Association (AMA)
Rajkumar, D. S. R.& Faitelson, A. V.& Gudyrev, O. S.& Dubrovin, G. M.& Pokrovskiy, Mihail V.& Ivanov, A. V.. Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background. Journal of Osteoporosis. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-463664
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463664