![](/images/graphics-bg.png)
Insulin Resistance, Inflammation, and Obesity : Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism
Joint Authors
Joven, Jorge
Rull, Anna
Camps, Jordi
Alonso-Villaverde, Carlos
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-23
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
To maintain homeostasis under diverse metabolic conditions, it is necessary to coordinate nutrient-sensing pathways with the immune response.
This coordination requires a complex relationship between cells, hormones, and cytokines in which inflammatory and metabolic pathways are convergent at multiple levels.
Recruitment of macrophages to metabolically compromised tissue is a primary event in which chemokines play a crucial role.
However, chemokines may also transmit cell signals that generate multiple responses, most unrelated to chemotaxis, that are involved in different biological processes.
We have reviewed the evidence showing that monocyte chemoattractant protein-1 (MCP-1 or CCL2) may have a systemic role in the regulation of metabolism that sometimes is not necessarily linked to the traffic of inflammatory cells to susceptible tissues.
Main topics cover the relationship between MCP-1/CCL2, insulin resistance, inflammation, obesity, and related metabolic disturbances.
American Psychological Association (APA)
Rull, Anna& Camps, Jordi& Alonso-Villaverde, Carlos& Joven, Jorge. 2010. Insulin Resistance, Inflammation, and Obesity : Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-463753
Modern Language Association (MLA)
Rull, Anna…[et al.]. Insulin Resistance, Inflammation, and Obesity : Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism. Mediators of Inflammation No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-463753
American Medical Association (AMA)
Rull, Anna& Camps, Jordi& Alonso-Villaverde, Carlos& Joven, Jorge. Insulin Resistance, Inflammation, and Obesity : Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-463753
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463753