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Chinese Herbal Medicine (Zi Shen Qing) for Mild-to-Moderate Systematic Lupus Erythematosus : A Pilot Prospective, Single-Blinded, Randomized Controlled Study
Joint Authors
Mao, Jian Chun
Tian, Yu
Gu, Jun Hua
Chen, Xiang Jun
Zhou, Xin
Zhong, Linda L. D.
Bian, Zhao Xiang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
The aim of this study is to investigate the effectiveness and safety of a Chinese herbal formula Zi Shen Qing (ZSQ) in the treatment of systematic lupus erythematosus (SLE) in Chinese patients.
Methods.
A randomized controlled trial was conducted over 12 weeks in 84 Chinese patients who reported total scores of SLE Disease Activity Index-2000 (SLEDAI-2000) was from 5 to 14.
The primary outcome was the changes of the SLEDAI-2000.
The secondary outcomes included score changes of Chinese Medicine Syndromes (CMS), the changes of steroid dosage, the incidence of disease flare-up and biologic markers.
Results.
ZSQ significantly reduced SLEDAI-2000, the total scores of CMS in the treatment group compared with the controlled group (P<0.05).
Superiority of ZSQ over controlled group was also observed with greater improvement in the withdrawal dosage of corticosteroids and the incidence of disease flare-up (P<0.05).
There were no serious adverse events, and safety indices of whole blood counts, renal and liver functions were normal, both before and after the treatment.
Conclusion.
ZSQ is safe and effective for decreasing SLE disease activity and withdrawal dosage of corticosteroids in the mild to moderate SLE patients with “Deficiency of Qi and Yin” Pattern.
American Psychological Association (APA)
Zhong, Linda L. D.& Bian, Zhao Xiang& Gu, Jun Hua& Zhou, Xin& Tian, Yu& Mao, Jian Chun…[et al.]. 2013. Chinese Herbal Medicine (Zi Shen Qing) for Mild-to-Moderate Systematic Lupus Erythematosus : A Pilot Prospective, Single-Blinded, Randomized Controlled Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-463814
Modern Language Association (MLA)
Zhong, Linda L. D.…[et al.]. Chinese Herbal Medicine (Zi Shen Qing) for Mild-to-Moderate Systematic Lupus Erythematosus : A Pilot Prospective, Single-Blinded, Randomized Controlled Study. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-463814
American Medical Association (AMA)
Zhong, Linda L. D.& Bian, Zhao Xiang& Gu, Jun Hua& Zhou, Xin& Tian, Yu& Mao, Jian Chun…[et al.]. Chinese Herbal Medicine (Zi Shen Qing) for Mild-to-Moderate Systematic Lupus Erythematosus : A Pilot Prospective, Single-Blinded, Randomized Controlled Study. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-463814
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463814