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Endothelial Function Increases after a 16-Week Diet and Exercise Intervention in Overweight and Obese Young Women
Joint Authors
Cotie, Lisa M.
Phillips, Stuart M.
MacDonald, Maureen J.
Josse, Andrea R.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-20
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Weight loss improves endothelial function in overweight individuals.
The effects of weight loss through combined aerobic and resistance training and caloric restriction on in vivo vascular measures and blood markers associated with the regulation of endothelial function have not been comprehensively examined.
Therefore, we investigated brachial artery endothelial function and potential regulatory blood markers in twenty overweight women (30.3 ± 2.0 years) who participated in 16 weeks of aerobic (5 d/wk) and resistance training (2 d/wk) (combined: ≥250 kcal/d) and caloric restriction (−500 kcal/d versus requirement).
Resting brachial artery flow mediated dilation (FMD) and circulating endothelin-1 (ET-1) and interleukin-6 (IL-6) were assessed at baseline and following the intervention.
Relative and absolute FMD increased (before: 4.0 ± 0.5% versus after: 6.9 ± 0.6%, P<0.05, and before: 0.14 ± 0.02 mm versus after: 0.23 ± 0.02 mm, P<0.05, resp.), while body mass decreased (before: 86.9 ± 2.4 kg versus after: 81.1 ± 2.4 kg, P<0.05) following the intervention.
There were no changes in either blood marker (IL-6: before: 1.5 ± 0.2 pg/mL versus after: 1.5 ± 0.1 pg/mL, P>0.05, and ET-1: before: 0.55 ± 0.05 pg/mL versus after: 0.59 ± 0.09 pg/mL, P>0.05).
16 weeks of combined aerobic/resistance training and diet-induced weight loss improved endothelial function in overweight and obese young women, but this increase was not associated with changes in blood markers of vasoconstriction or inflammation.
American Psychological Association (APA)
Cotie, Lisa M.& Josse, Andrea R.& Phillips, Stuart M.& MacDonald, Maureen J.. 2014. Endothelial Function Increases after a 16-Week Diet and Exercise Intervention in Overweight and Obese Young Women. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-463836
Modern Language Association (MLA)
Cotie, Lisa M.…[et al.]. Endothelial Function Increases after a 16-Week Diet and Exercise Intervention in Overweight and Obese Young Women. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-463836
American Medical Association (AMA)
Cotie, Lisa M.& Josse, Andrea R.& Phillips, Stuart M.& MacDonald, Maureen J.. Endothelial Function Increases after a 16-Week Diet and Exercise Intervention in Overweight and Obese Young Women. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-463836
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463836