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Lymphoma of the Urinary Bladder
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-09
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Background.
Lymphoma of the urinary bladder (LUB) is rare.
Aims.
To review the literature on LUB.
Methods.
Various internet databases were used.
Results.
LUB can be either primary or secondary.
The tumour has female predominance; most cases occur in middle-age women.
Secondary LUB occurs in 10% to 25% of leukemias/lymphomas and in advanced-stage systemic lymphoma.
Less than 100 cases have been reported.
MALT typically affects adults older than 60 years; 75% are female.
Diffuse large B-cell lymphoma is also common and may arise from transformation of MALT.
LUB presents with haematuria, dysuria, urinary frequency, nocturia, and abdominal or back pain.
Macroscopic examination of LUBs show large discrete tumours centred in the dome or lateral walls of the bladder.
Positive staining of LUB varies by the subtype of lymphoma; B-cell lymphomas are CD20 positive.
MALT lymphoma is positively stained for CD20, CD19, and FMC7 and negatively stained for CD5, CD10, and CD11c.
LUB stains negatively with Pan-keratin, vimentin, CK20, and CK7.
MALT lymphoma exhibits t(11; 18)(q21: 21).
Radiotherapy is an effective treatment for the MALT type of LUB with no recurrence.
Conclusions.
LUB is diagnosed by its characteristic morphology and immunohistochemical characteristics.
Radiotherapy is a useful treatment.
American Psychological Association (APA)
Venyo, Anthony Kodzo-Grey. 2014. Lymphoma of the Urinary Bladder. Advances in Urology،Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-463878
Modern Language Association (MLA)
Venyo, Anthony Kodzo-Grey. Lymphoma of the Urinary Bladder. Advances in Urology No. 2014 (2014), pp.1-19.
https://search.emarefa.net/detail/BIM-463878
American Medical Association (AMA)
Venyo, Anthony Kodzo-Grey. Lymphoma of the Urinary Bladder. Advances in Urology. 2014. Vol. 2014, no. 2014, pp.1-19.
https://search.emarefa.net/detail/BIM-463878
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463878