Influence of Triatoma dimidiata in Modulating the Virulence of Trypanosoma cruzi Mexican Strains
Joint Authors
Ortega-Pacheco, Antonio
Guzmán-Marín, Eugenia del S.
Jiménez-Coello, Matilde
Puerto-Solis, M.
Acosta Viana, Karla Y.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The epidemiology of Chagas disease is complex.
There are different vectors and reservoirs and different clinical manifestations.
In order to assess whether the biological behavior of three strains isolated in southeastern Mexico (H4 isolated from human, Z17 isolated from Didelphis sp., and V isolated from T.
dimidiata) could be modified during passage through the vector T.
dimidiata, the parasitemia curve, the amount of amastigote nests, and mortality of BALB/c infected with blood trypomastigotes of T.
cruzi were evaluated.
Strains were maintained in continuous passage from mouse to mouse and in animals infected with metacyclic trypomastigotes.
The parasitemia curves were significantly different (P<0.05) between mice to mice and triatoma to mice groups in strains H4 and Z17, and was also observed fewer amastigote nests in cardiac tissue (P<0.05 strain H4 with higher number versus all groups and Z17 between mice to mice and triatoma to mice) 45 days after inoculation.
It is concluded that T.
dimidiata influences in modulating the virulence of strains of T.
cruzi in the region.
Further studies of the intestinal tract of the insect in search for some protein molecules involved in regulating may clarify the virulence of the parasite.
American Psychological Association (APA)
Guzmán-Marín, Eugenia del S.& Jiménez-Coello, Matilde& Puerto-Solis, M.& Ortega-Pacheco, Antonio& Acosta Viana, Karla Y.. 2012. Influence of Triatoma dimidiata in Modulating the Virulence of Trypanosoma cruzi Mexican Strains. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463893
Modern Language Association (MLA)
Guzmán-Marín, Eugenia del S.…[et al.]. Influence of Triatoma dimidiata in Modulating the Virulence of Trypanosoma cruzi Mexican Strains. Interdisciplinary Perspectives on Infectious Diseases No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-463893
American Medical Association (AMA)
Guzmán-Marín, Eugenia del S.& Jiménez-Coello, Matilde& Puerto-Solis, M.& Ortega-Pacheco, Antonio& Acosta Viana, Karla Y.. Influence of Triatoma dimidiata in Modulating the Virulence of Trypanosoma cruzi Mexican Strains. Interdisciplinary Perspectives on Infectious Diseases. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463893
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463893