Protein Kinases and Phosphatases in the Control of Cell Fate
Joint Authors
De Marchi, Elena
Poletti, Federica
Rimessi, Alessandro
Missiroli, Sonia
Pinton, Paolo
Bononi, Angela
Agnoletto, Chiara
Bonora, Massimo
Giorgi, Carlotta
Marchi, Saverio
Patergnani, Simone
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-26, 26 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-04
Country of Publication
Egypt
No. of Pages
26
Main Subjects
Abstract EN
Protein phosphorylation controls many aspects of cell fate and is often deregulated in pathological conditions.
Several recent findings have provided an intriguing insight into the spatial regulation of protein phosphorylation across different subcellular compartments and how this can be finely orchestrated by specific kinases and phosphatases.
In this review, the focus will be placed on (i) the phosphoinositide 3-kinase (PI3K) pathway, specifically on the kinases Akt and mTOR and on the phosphatases PP2a and PTEN, and on (ii) the PKC family of serine/threonine kinases.
We will look at general aspects of cell physiology controlled by these kinases and phosphatases, highlighting the signalling pathways that drive cell division, proliferation, and apoptosis.
American Psychological Association (APA)
Bononi, Angela& Agnoletto, Chiara& De Marchi, Elena& Marchi, Saverio& Patergnani, Simone& Bonora, Massimo…[et al.]. 2011. Protein Kinases and Phosphatases in the Control of Cell Fate. Enzyme Research،Vol. 2011, no. 2011, pp.1-26.
https://search.emarefa.net/detail/BIM-463984
Modern Language Association (MLA)
Bononi, Angela…[et al.]. Protein Kinases and Phosphatases in the Control of Cell Fate. Enzyme Research No. 2011 (2011), pp.1-26.
https://search.emarefa.net/detail/BIM-463984
American Medical Association (AMA)
Bononi, Angela& Agnoletto, Chiara& De Marchi, Elena& Marchi, Saverio& Patergnani, Simone& Bonora, Massimo…[et al.]. Protein Kinases and Phosphatases in the Control of Cell Fate. Enzyme Research. 2011. Vol. 2011, no. 2011, pp.1-26.
https://search.emarefa.net/detail/BIM-463984
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463984