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Imidazole : Having Versatile Biological Activities
Joint Authors
Verma, Amita
Singh, Deepika
Joshi, Sunil
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-31
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Imidazoles have occupied a unique position in heterocyclic chemistry, and its derivatives have attracted considerable interests in recent years for their versatile properties in chemistry and pharmacology.
Imidazole is nitrogen-containing heterocyclic ring which possesses biological and pharmaceutical importance.
Thus, imidazole compounds have been an interesting source for researchers for more than a century.
The imidazole ring is a constituent of several important natural products, including purine, histamine, histidine, and nucleic acid.
Being a polar and ionisable aromatic compound, it improves pharmacokinetic characteristics of lead molecules and thus is used as a remedy to optimize solubility and bioavailability parameters of proposed poorly soluble lead molecules.
There are several methods used for the synthesis of imidazole-containing compounds, and also their various structure reactions offer enormous scope in the field of medicinal chemistry.
The imidazole derivatives possess extensive spectrum of biological activities such as antibacterial, anticancer, antitubercular, antifungal, analgesic, and anti-HIV activities.
This paper aims to review the biological activities of imidazole during the past years.
American Psychological Association (APA)
Verma, Amita& Joshi, Sunil& Singh, Deepika. 2013. Imidazole : Having Versatile Biological Activities. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-464018
Modern Language Association (MLA)
Verma, Amita…[et al.]. Imidazole : Having Versatile Biological Activities. Journal of Chemistry No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-464018
American Medical Association (AMA)
Verma, Amita& Joshi, Sunil& Singh, Deepika. Imidazole : Having Versatile Biological Activities. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-464018
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464018