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Higher Cortisol Predicts Less Improvement in Verbal Memory Performance after Cardiac Rehabilitation in Patients with Coronary Artery Disease
Joint Authors
Kiss, Alexander
Swardfager, Walter
Koren, Gideon
Saleem, Mahwesh
Van Uum, Stanislaus H. M.
Lanctôt, Krista L.
Oh, Paul I.
Shammi, Prathiba
Herrmann, Nathan
Source
Cardiovascular Psychiatry and Neurology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
While physical activity can improve verbal memory performance in subjects with coronary artery disease (CAD), there is large variability in response.
Elevated cortisol production has been suggested to negatively affect verbal memory performance, yet cortisol concentrations have not been assessed as a predictor of response to exercise intervention in those with CAD.
Methods.
CAD patients participating in a one-year cardiac rehabilitation program were recruited.
Memory was assessed with the California Verbal Learning Test second edition at baseline and one year.
Cortisol was measured from a 20 mg, 3.0 cm hair sample collected at baseline.
Results.
In patients with CAD (n=56, mean ± SD age = 66±11, 86% male), higher cortisol (hair cortisol concentrations ≥ 153.2 ng/g) significantly predicted less memory improvement (F1,50=5.50, P=0.02) when controlling for age (F1,50=0.17, P=0.68), gender (F1,50=2.51, P=0.12), maximal oxygen uptake (F1,50=1.88, P=0.18), and body mass index (F1,50=3.25, P=0.08).
Conclusion.
Prolonged hypothalamic pituitary adrenal axis activation may interfere with exercise-related improvements in memory in CAD.
American Psychological Association (APA)
Saleem, Mahwesh& Herrmann, Nathan& Swardfager, Walter& Oh, Paul I.& Shammi, Prathiba& Koren, Gideon…[et al.]. 2013. Higher Cortisol Predicts Less Improvement in Verbal Memory Performance after Cardiac Rehabilitation in Patients with Coronary Artery Disease. Cardiovascular Psychiatry and Neurology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-464116
Modern Language Association (MLA)
Saleem, Mahwesh…[et al.]. Higher Cortisol Predicts Less Improvement in Verbal Memory Performance after Cardiac Rehabilitation in Patients with Coronary Artery Disease. Cardiovascular Psychiatry and Neurology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-464116
American Medical Association (AMA)
Saleem, Mahwesh& Herrmann, Nathan& Swardfager, Walter& Oh, Paul I.& Shammi, Prathiba& Koren, Gideon…[et al.]. Higher Cortisol Predicts Less Improvement in Verbal Memory Performance after Cardiac Rehabilitation in Patients with Coronary Artery Disease. Cardiovascular Psychiatry and Neurology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-464116
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464116