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Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy
Joint Authors
Bullen, Heather A.
Haik, Kristi L.
Fabré, Thomas A.
Buhrlage, Andrew
Cason, Chevelle A.
Source
International Journal of Analytical Chemistry
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Immunoimaging scanning probe microscopy was utilized for the low-level detection and quantification of biotinylated G4 poly(amidoamine) PAMAM dendrimers.
Results were compared to those of high-performance liquid chromatography (HPLC) and found to provide a vastly improved analytical method for the low-level detection of dendrimers, improving the limit of detection by a factor of 1000 (LOD=2.5×10−13 moles).
The biorecognition method is reproducible and shows high specificity and good accuracy.
In addition, the capture assay platform shows a promising approach to patterning dendrimers for nanotechnology applications.
American Psychological Association (APA)
Cason, Chevelle A.& Fabré, Thomas A.& Buhrlage, Andrew& Haik, Kristi L.& Bullen, Heather A.. 2012. Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy. International Journal of Analytical Chemistry،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-464211
Modern Language Association (MLA)
Cason, Chevelle A.…[et al.]. Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy. International Journal of Analytical Chemistry No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-464211
American Medical Association (AMA)
Cason, Chevelle A.& Fabré, Thomas A.& Buhrlage, Andrew& Haik, Kristi L.& Bullen, Heather A.. Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy. International Journal of Analytical Chemistry. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-464211
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464211